Marklip: Biodegradable marker clip
- Product:
A flexible marker cylinder, 1mm thick and 5-10mm length, which can be seen in MRI, US, and CT. It is made of biodegradable polymer PLGA which is FDA approved and is used in numerous devices in clinical use. - Key features:
- Made from FDA approved components (PLA, Lipiodol, Fe2O3)
- Visible by all medical imaging devices
- Designed into different shapes
- Can serve as marker for breast, colorectal, other tissues
- Theragnostic-may contain a drug for local delivery
- Use case:
Mammography (replacing existing metallic marker clips) - Current state:
- Patent-protected (PCT)
- Prototype has been successfully tested on animals, ready for preclinical and human studies
- Product:
PolyGel: Biodegradable polymer gel
Polygene’s proprietary injectable biodegradable polymer gel is available as carrier for the delivery of bioactive agents for weeks after a single injection. Bioactive agents, including proteins and RNA, are incorporated in the pasty polymer by gentle mixing at room temperature for IM or SC injection. The polymer is currently in clinical development for the delivery of anticancer agents (https://www.intra-gel.com) and antibiotics by Gentagel LR (https://gentagel-lr.com).
PolyGel is available for indications other than Cancer and Bacterial infections. PolyGel is also available as tissue filler and for non-medical applications.
ProNanoLipid: Nano-lipid dispersible solid
Polygene’s proprietary solid lipid formulation that forms a nano-dispersion upon adding to water. ProNanoLipid intended use is for the delivery of lipid soluble bioactive agents. ProNanoLipid is currently in clinical development for improved oral bioavailability of cannabinoids.
